This zwitterionic representative of well known PEGylated undecanethiol gold standard is an interesting example of novel ultra-non-fouling SAM building-block. As demonstrated by Akash Gupta and colleagues it provides high colloidal stability to medium and large gold nanoparticles while maintaining their low unspecific protein binding even in undiluted body fluids.
Carboxybetaine termination supports further attachment of macromolecules including proteins and polypeptides, enabling a simple "plug and play" strategy. Additionally the nanoparticles stabilised with this molecule exhibit robust resistance to freeze-dry and changes in ionic strength over wide range, while still maintaining functionalization capabilities (Ultra-stable Biofunctionalizable Gold Nanoparticles, ACS Appl. Mater. Interfaces, 2016, 8, 14096–14101).
Great, emerging class of bioresistant molecules ProChimia is offering just now.
|HS-C11-EG4-Carboxybetaine||ZI 003-m11.n4-0.1||11||4||100 mg||Log in to see the prices|
|HS-C11-EG4-Carboxybetaine||ZI 003-m11.n4-0.2||11||4||200 mg|
|HS-C11-EG4-Carboxybetaine||ZI 003-m11.n4-0.5||11||4||500 mg|
|HS-C11-EG4-Carboxybetaine||ZI 003-m11.n4-1||11||4||1 g|
This product is also available on custom synthesis basis, in the following variants:
m: 10, 16
n: 2, 3, 6
Note, if none of the listed structures fit your specific requirements, please submit your own structure formula within our custom synthesis contact form by clicking button below.