Most usually the initial pioneer route of synthesis used to prepare a few milligrams of unique molecule is not suitable to prepare hundreds or even thousands of grams of commercially available target compound. ProChimia experienced staff will redesign and adapt given synthesis to smart, tailored process that fits in changing demands.
Many already existing synthetic processes still include some problematic transitions or steps missing superior optimalisation. ProChimia offers a comprehensive process development services supported by both: unique in silico tools and in-house team experience. Our carefully evolved procedure covers all aspects of rational synthetic process development. We research and select critical parameters of the process, reaction progress, kinetics, byproducts/impurities profile and respective purification issues. All this efforts assisted by suited analytics lead to supreme process control and performance.
Reproducing a demonstrated route of synthesis in a large scale is most likely a complex matter that requires industrial technology know-how besides theory and laboratory skills. Along the scaling up Prochimia specialists will identify and solve the issues referring to scale, methodology, safety and environment. We have an experience in transferring scaled up processes to a GMP-certified production plants.
Based on years of continuous production experience and shared intellectual resources, ProChimia offers and deliver high quality chemicals and key components on the basis of Supply Contracts to several business partners.