Description

This simple variant of Carboxybetaine terminated SAM (please see also cat no. ZI 003-m11) was successfully used to immobilise lectins and construct non fouling sensor aiming glycoprofiling of antibodies isolated from healthy individuals and rhematoid arthritis patients. (Carboxybetaine Modified Interface for Electrochemical Glycoprofiling of Antibodies Isolated from Human Serum, Langmuir, 2015, 31, 7148-7157)
(Stealth Surface Modification of Surface-Enhanced Raman Scattering Substrates for Sensitive and Accurate Detection in Protein Solutions, ACS Nano, 2015, 9 (3), 2668–2676)
Prof Shaoyi group have also demonstrated extraordinary non-fouling capabilities of carboxybetaine moiety in a new polycarboxybetaine - pluronic copolymeric approach for zwitterionic surfaces. (Simple and Robust Approach for Passivating and Functionalizing Surfaces for Use in Complex Media, Langmuir 2012, 28, 9707−9713, 2016)