Harbors molecules onto a SAM-covered surface though an amide bond forming between the NHS ester and the molecule's free amino group. This NHS-ester coupling reaction is extremely easy to carry out, and proceeds in excellent yield. In a typical procedure, a gold slide (~1 cm2) covered with NHS-terminated SAM is immersed for 3 hrs in 0.5 mL of a methylene chloride (chloroform, THF, dry DMF and DMSO, absolute ethanol are also allowed) solution of a molecule bearing free amino group and 1.5 equivalents of NEt3. When the reaction is complete, the substrate should be rinsed with pure solvent and dried under a stream of nitrogen.
name | catalog no. | m | n | weight | price |
---|---|---|---|---|---|
HS-C10-COO-NHS | FT 003-m10-0.2 | 10 | 200 mg | Log in to see the prices | |
HS-C10-COO-NHS | FT 003-m10-0.5 | 10 | 500 mg | ||
HS-C10-COO-NHS | FT 003-m10-1 | 10 | 1 g | ||
HS-C11-COO-NHS | FT 003-m11-0.1 | 11 | 100 mg | ||
HS-C11-COO-NHS | FT 003-m11-0.2 | 11 | 200 mg | ||
HS-C11-COO-NHS | FT 003-m11-0.5 | 11 | 500 mg | ||
HS-C11-COO-NHS | FT 003-m11-1 | 11 | 1 g | ||
HS-C15-COO-NHS | FT 003-m15-0.2 | 15 | 200 mg | ||
HS-C15-COO-NHS | FT 003-m15-0.5 | 15 | 500 mg | ||
HS-C15-COO-NHS | FT 003-m15-1 | 15 | 1 g |
This product is also available on custom synthesis basis, in the following variants:
n: n/a
Note, if none of the listed structures fit your specific requirements, please submit your own structure formula within our custom synthesis contact form by clicking button below.