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HS-(CH2)m-COO-NHS (FT 003)


Harbors molecules onto a SAM-covered surface though an amide bond forming between the NHS ester and the molecule's free amino group. This NHS-ester coupling reaction is extremely easy to carry out, and proceeds in excellent yield. In a typical procedure, a gold slide (~1 cm2) covered with NHS-terminated SAM is immersed for 3 hrs in 0.5 mL of a methylene chloride (chloroform, THF, dry DMF and DMSO, absolute ethanol are also allowed) solution of a molecule bearing free amino group and 1.5 equivalents of NEt3. When the reaction is complete, the substrate should be rinsed with pure solvent and dried under a stream of nitrogen.

Standard Products

name catalog no. m n weight price
HS-C10-COO-NHS FT 003-m10-0.2 10 200 mg Log in to see the prices
HS-C10-COO-NHS FT 003-m10-0.5 10 500 mg
HS-C10-COO-NHS FT 003-m10-1 10 1 g
HS-C11-COO-NHS FT 003-m11-0.1 11 100 mg
HS-C11-COO-NHS FT 003-m11-0.2 11 200 mg
HS-C11-COO-NHS FT 003-m11-0.5 11 500 mg
HS-C11-COO-NHS FT 003-m11-1 11 1 g
HS-C15-COO-NHS FT 003-m15-0.2 15 200 mg
HS-C15-COO-NHS FT 003-m15-0.5 15 500 mg
HS-C15-COO-NHS FT 003-m15-1 15 1 g

Custom synthesis variants

Note, if none of the listed structures fit your specific requirements, please submit your own structure formula within our custom synthesis contact form by clicking button below.

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