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Au-S-(CH2)11-NH-C(O)-Biotin
Au-S-(CH2)11-NH-C(O)-Biotin (NP BS 001-075)

Description

Biotinylated thiols coating these NPs bind very tightly (Kd ~ 10-15!) and specifically to streptavidin and avidin constructs (for review, see Angew. Chem. Int. Ed. 2004, 43, 6042).In addition to affinity-binding applications, biotinylated AuNPs have been used for programmed assembly of nanostructured materials (Adv. Mater. 1999, 11, 1202; Langmuir 2005, 21, 10756), in optical biochemical sensors (Anal. Chem. 2003, 75, 16), to study plasmon-exciton interactions in mixtures of semiconductor and gold NPs (Nano Lett., 2004, 4, 2323) and as components of protein microarrays (Anal. Chem. 2005, 77, 5770). For more examples of applications, see Chem. Rev. 2004, 104, 293.


Metal

Au

Ligand

HS-(CH2)11-NH-C(O)-Biotin

SPR Maximum

518-524

Solubility

H2O



Standard Products

name catalog no. size color dispersity volume concentration price
Au_55_C11Biotin NP BS 001-075 5.5nm red 10% 7.5mL 2.4 x 1014 NPs/mL Log in to see the prices
Au_55_C11Biotin NP BS 001-150 5.5nm red 10% 15mL 2.4 x 1014 NPs/mL

Custom synthesis variants

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